Bilateral pure gonadoblastoma in a 46 XY individual--a case report.
نویسندگان
چکیده
We report here a rare case of bilateral pure gonadoblastoma which accounts for only 0.2% of all ovarian tumours seen at Universiti Kebangsaan Malaysia from 1980 to 1987. This tumour occurred in an 18 year old Chinese "female" who presented with primary amenorrhoea. Examination showed a phenotypic female with poorly developed external gentalia. Exploratory laparotomy revealed a hypoplastic uterus, rudimentary fallopian tubes and streak gonads. Histological examination of the gonads showed a mixed tumour comprising large germ cells and smaller sex cord derivatives arranged in characteristic nests or islands containing hyaline material.
منابع مشابه
Bilateral gonadoblastoma/dysgerminoma in a 46 XY individual: case report with hormonal studies.
A case of bilateral gonadoblastoma/dysgerminoma in a 46 XY phenotypical female is presented. Increased circulating beta human chorionic gonadotropin (beta-HCG) and testosterone together with a decreased concentration of follicle stimulating hormone (FSH) reflected the activities of these tumours. The patient is alive and well three years later, after treatment by surgery and cobalt therapy.
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متن کامل46,XY female sex reversal syndrome with bilateral gonadoblastoma and dysgerminoma
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عنوان ژورنال:
- The Medical journal of Malaysia
دوره 46 4 شماره
صفحات -
تاریخ انتشار 1991